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- Title
THE ACTION OF SALICYLATE, DINITROPHENOL AND CARDIAC GLYCOSIDES ON THE ISOLATED TOAD HEART.
- Authors
Nayler, Winifred G.
- Abstract
The actions of sodium salicylate (5 mM final concentration) and of D.N.P. (1.09 x 10-5 final concentration) on the isolated perfused toad's heart have been studied. Both drugs caused marked stimulation of oxidative metabolism. The inotropic action of the glycosides in the presence of these two metabolic inhibitors was studied. Pre-treatment of the hearts with D.N.P. or salicylate abolished the inotropic response.
- Publication
Australian Journal of Experimental Biology & Medical Science, 1957, Vol 35, Issue 5, p491
- ISSN
0004-945X
- Publication type
Academic Journal
- DOI
10.1038/icb.1957.51