We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role of Neurotrophic Factors BDNF and GDNF in Nervous System Adaptation to the Influence of Ischemic Factors.
- Authors
Mitroshina, E. V.; Mishchenko, T. A; Shishkina, T. V.; Vedunova, M. V.
- Abstract
We developed a complex in vitro model of ischemic damage. Analysis of hippocampal cell viability in primary cultures after modeling of various stress factors revealed the features of action of the main pathological factors of ischemia. Neurotrophic factors BDNF and GDNF produced pronounced neuroprotective effect during modeling both the complex ischemic damage and its individual pathophysiological components. Neurotrophic factor GDNF produced the most pronounced protective effect.
- Publication
Bulletin of Experimental Biology & Medicine, 2019, Vol 167, Issue 4, p574
- ISSN
0007-4888
- Publication type
Academic Journal
- DOI
10.1007/s10517-019-04574-1