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- Title
Prevalence and Clinical Outcome of Inpatient Hyperglycemia in a Community Pediatric Hospital.
- Authors
Palacio, Andres; Smiley, Dawn D.; Ceron, Miguel; Klein, Robin; Cho, Irene; Mejia, Roberto; Umpierrez, Guillermo E.
- Abstract
Observational studies in adult subjects have shown that inpatient hyperglycemia is a predictor of poor clinical outcome. No previous studies; however, have examined the association of hyperglycemia and clinical outcome in children admitted to a general community pediatric hospital. Retrospective observational cohort of pediatric patients admitted to a single community children's Hospital, from 1/2004 to 8/2004. Medical records of 903 consecutive children admitted to critical and non-critical care areas were reviewed. Of them, 342 patients (38%) had no blood glucose measurements during the hospital stay; the remaining 561 patients were divided according to a prior history of DM and admission BG level. We determined the prevalence of hyperglycemia and examined the association of hyperglycemia and clinical outcome. A total of 406 patients (75.1%) had an admission BG ≤ 120 mg/dl [(mean 98 ± 1 mg/dl (± SEM)], 103 children (19%) with BG between 121-179 mg/dl (mean 143 ± 2 mg/dl) and 32 patients (5.9%) with a BG ≥ 180 mg/dl (mean 260 ± 18 mg/dl). Most children admitted with hyperglycemia had no previous history of diabetes prior to admission. Only 17 patients (13%) had a known history of diabetes prior to admission. Hyperglycemia in children without a history of diabetes was frequently untreated (1.1% of children with BG 120-179 mg/dl and 20% of those with BG > 180 mg/dl received insulin therapy). Children with hyperglycemia were more likely to be admitted to the ICU (p<.001), and had a longer length of ICU stay (p<.001), but admission hyperglycemia was not associated with longer hospital length of stay or higher hospital mortality. Hyperglycemia was present in one-fourth of the children admitted to the hospital, most of them without a history of diabetes prior to admission. Hyperglycemia was associated with a greater need for ICU care and longer ICU stay but not with longer hospital stay or increased in-hospital mortality.
- Publication
Diabetes, 2007, Vol 56, pA654
- ISSN
0012-1797
- Publication type
Academic Journal