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- Title
Grape seed extract mouthrinse (Vitis Vinifera) as a herbal antiplaque agent.
- Authors
Rodrigues, Silvia; Talati, Meenakshi; Mitra, Dipika; Shah, Rohit; Shetty, Gaurav; Vijaykar, Harshad; Prithyani, Saurabh
- Abstract
Brief Background Grapes are scientifically known as vitis vinifera. Their seeds are rich in phenolic compounds, with an ability to damage microbial cells by exerting an influence on the selective permeability of the plasma membrane. This results in the leakage of vital intracellular substances and may be used as antibacterial agents for dental use. Aims and Objective To evaluate the antiplaque efficacy of grape seed extract mouth rinse as compared to chlorhexidine and distilled water in a four-day plaque regrowth model and evaluate its antibacterial properties against selected periodontopathogens invitro. Materials and Mathods Seventy-five periodontally healthy volunteers, underwent oral prophylaxis after which they refrained from oral hygiene measures for 4 days. They were assigned to one of the 3 groups (A grape seed extract; B chlorhexidine; C distilled water) twice daily. Plaque Index (PI) and Gingival Index(GI) were assessed at days 0 and 5. Invitro Grape seed extract was tested against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Results Grape seed extract showed better results both invitro and invivo as compared to distilled water. However, it was not the same when compared to chlorhexidine. Summary and Conclusions Grape seed extract showed better results both invitro and invivo as compared to distilled water. However, it was not the same when compared to chlorhexidine.
- Publication
JIDA: Journal of Indian Dental Association, 2018, Vol 12, Issue 9, p27
- ISSN
0019-4611
- Publication type
Academic Journal