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- Title
Antibacterial activity of Green Tea Extract against cariogenic Streptococcus mutans - In vitro study.
- Authors
Bhat, Sham; Hegde, Sundeep K.; Rao, Ajay; Natasha, Amanna Evette
- Abstract
Brief Background There is an increasing demand for use of medicinal plants having antibacterial property and green tea is a nonfermented tea which is one of the ancient and popular therapeutic beverages consumed around the world. Aim Dental plaque plays an important role in the development of dental carie, Streptococcus mutans being the bacteria in dental plaque. The purpose of the study was to evaluate the activity of green tea extract against Streptococcus mutans. Materials and Methods Bacterial strains of Streptococcus mutans MTCC 890 was used in this study, which was cultured in trypticase soy broth. The antibacterial activity of green tea extract was determined as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) using Broth dilution method. The rates at which bacteria were killed were also assessed by exposure to the extract at 2xMBC and 4x MBC for varying time periods Results Green tea extract was effective against strain of Streptococcus mutans MTCC 890. The MIC and MBC for the extract was 3.125mg/ml and 6.25mg/ml respectively. Time-kill assays for the extract at 2x MBC and 4x MBC caused a significant decrease in viable count (log10 colony forming units/ml) at varying time periods. Statistical analysis was done using one way analysis of variance (ANOVA), followed by Dunnettus post hoc test. Summary and Conclusions Green tea extract possessed antibacterial activity against Streptococcus mutans and the results suggest that the extract may be introduced as a new agent for dental plaque control and caries prevention.
- Publication
JIDA: Journal of Indian Dental Association, 2013, Vol 7, Issue 5, p28
- ISSN
0019-4611
- Publication type
Academic Journal