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- Title
The Effects of Fatty Acids and Their Monoesters on the Metabolic Activity of Dental Plaque.
- Authors
HAYES, M. L.
- Abstract
We examined the effects of the saturated series of fatty acids and their esters on plaque bacterial metabolism. Fatty acids with a chain length of 8-15 carbons inhibited Streptococcus mutans and dental plaque in vitro. The glycerol monoesters with a fatty acid chain of 10-14 carbons were inhibitory to a similar extent. The glycolipid (sucrose monolaurate) reduced plaque bacterial glycolysis and sucrose oxidation in a non-competitive manner but stimulated sucrose incorporation at low sucrose concentrations. The relationship between surface activity and inhibition is discussed, since this may help to explain the anti-caries effects of these compounds.
- Publication
Journal of Dental Research, 1984, Vol 63, Issue 1, p2
- ISSN
0022-0345
- Publication type
Academic Journal
- DOI
10.1177/00220345840630010301