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- Title
Inhibition of Axon Reflex Vasodilatation by Topically Applied Capsaicin.
- Authors
Bernstein, Joel E.; Swift, Robert M.; Soltani, Keyoumars; Lorincz, Allan L.
- Abstract
Topical application of capsaicin to human skin produced an initial burning erythematous reaction which diminished over 24 hr leaving the skin unresponsive to histamine-induced axon reflex vasodilatation without altering sensitivity to pain, touch and temperature. Depletion of substance P from local sensory nerve terminals is suggested as a possible explanation for this capsaicin effect.
- Publication
Journal of Investigative Dermatology, 1981, Vol 76, Issue 5, p394
- ISSN
0022-202X
- Publication type
Academic Journal
- DOI
10.1111/1523-1747.ep12520912