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- Title
Catalase antioxidant activity and nutritional status in anorexia nervosa.
- Authors
Oliveras López, M. J.; Martín Bermudo, F.; De la Cerda Bardallo, F.; Jaúregui Lobera, I.
- Abstract
Introduction: There is a shortage of studies focused on the antioxidant status among patients with anorexia nervosa. As far as we know there are not any follow-up studies aimed to relate changes in that status with the renutrition treatment of those patients. Objectives: The aim of the current study was to determine the catalase activity in anorexia nervosa at the beginning of the treatment as well as when patients recovered a normal body mass index (BMI ± 18.5). Methods:A total of 25 outpatients were studied (mean age 19.2) who fulfilled the DSM-IV-RT criteria for anorexia nervosa. Haematological and biochemical parameters as well as the nutritional intake were determined within the first week of the treatment (M0) and after gaining weight to re establish a normal body mass index (M1). Plasma samples were obtained and the activity of catalase was measured by spectrophotometric assays. Results: Mean time to recovery was 4.1 ± 2.44 months. Overall the catalase activity increased significantly (M0 = 25.03 } 9.85; M1 = 35.54 ± 13.01; p < 0.0001). There was a significant difference between patients with a rapid recovery (≤ 3 months) and the rest (+16.14 vs. + 4.4 respectively; p < 0.01). Our results support an association between the nutritional status in patients with anorexia nervosa and the increase of the antioxidant activity of catalase.
- Publication
Nutrición Hospitalaria, 2012, Vol 27, p85
- ISSN
0212-1611
- Publication type
Academic Journal