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- Title
Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates.
- Authors
Anjum Zia, Muhammad; Faisal, Rana; Zahid Abbas, Rao; Gull-e-Faran; Kashif Saleemi, Muhammad; Junaid Ali Khan
- Abstract
Streptokinase is a novel bacterial fibrinolytic enzyme that binds and activates plasminogen and is produced by several species of Streptococci. Streptococcus mutans was selected for optimum production of streptokinase using corn steep liquor, molasses, rice polishing and sugarcane bagass in liquid state fermentation. Substrates were applied in different concentrations ranging from 0.1-0.8%. Maximum fibrinolytic activity was observed by 0.3% corn steep liquor, 0.5% molasses and rice polishing and 0.4% by sugarcane bagass. The fibrinolytic activity achieved by fibrin clot lysis method was 5.5, 5.08, 5.16 and 4.75 units using corn steep liquor, molasses, rice polishing and sugarcane bagass, respectively.
- Publication
Pakistan Veterinary Journal, 2013, Vol 33, Issue 1, p77
- ISSN
0253-8318
- Publication type
Academic Journal