We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Značaj humanih papiloma virusa u nastanku karcinoma glave i vrata.
- Authors
Božić, Ljiljana; Jovičić, Sanja; Šmitran, Aleksandra
- Abstract
Head and neck cancers (HNC) are a heterogeneous group of diseases. Histopathological, these are head and neck squamous cell carcinoma (HNSCC) epithelium of the skin, mucosa of the upper aerodigestive tract, pharynx and larynx. HNSCC is the fifth leading cause of cancer worldwide. The most important risk factors are alcohol and smoking. In the recent years, the studies have been conducted in order to prove the role of HPV in HNSCC carcinogenesis. The prevalence of HPV in HNSCC is 30%. HPV is often detected in biological materials of males. People with HPV positive HNSCC respond better to treatment and have a better treatment outcome than patients with no proven HPV. In the future, HPV should be the marker that will influence the choice of therapy in patients with HNSCC, but also the factor that will indicate the outcome of this malignancy in the human population.
- Publication
Scripta Medica, 2016, Vol 47, Issue 1, p69
- ISSN
0350-8218
- Publication type
Academic Journal
- DOI
10.18575/msrs.sm.s.16.12