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- Title
229: Salvage Cryotherapy for recurrent prostate cancer after radiation failure: The first 100 patients.
- Authors
Sood, Ashwani K.; Ismail, Mohamed; Davies, John H.
- Abstract
Introduction: In this study we report our experience evaluating the biochemical outcome and complications after salvage cryotherapy of the prostate. Methods: Between May 2000 and November 2005,100 patients underwent salvage cryoablation of the prostate. The mean follow-up was 21.6 months (range 3-67 months). The mean age was 67 years (range 54-78 years). All patients had biopsy proven recurrent prostate cancer. Two cryotherapy systems were used, Cryocare n=45 and Seednet n=55. Biochemical recurrence free survival was defined as PSA level < 0.5 ng/ml. Patients were stratified into 3 risk groups according to the following factors: PSA level, Gleason score and clinical stage. Results: There were no operative or cancer related mortalities. Sixty one patients received hormonal therapy prior to their cryosurgery. Cumulative biochemical recurrence free survival was 71% at 12 months, and 55% at 24 months. Five patients had redo cryosurgery. Complications included incontinence (11%). Erectile dysfunction (87%), lower urinary tract symptoms (15.5%), prolonged perineal pain (4%), urinary retention 2% and rectovesical fistula 1%. Conclusions: Our data supports the safety and efficacy of salvage cryotherapy with low morbidity rates. Cryosurgery should be considered as a therapeutic option in selected group of patients with localised recurrent prostate cancer.
- Publication
Indian Journal of Urology, 2008, Vol 24, pS126
- ISSN
0970-1591
- Publication type
Academic Journal