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- Title
Preliminary study on antirheumatic activity of curcumin (diferuloyl methane).
- Authors
Dcodhar, S. D.; Sethi, R.; Srimal, R. C.
- Abstract
A short term, double blind, cross-over study was carried out in 18 patients with 'definite' rheumatoid arthritis to compare the antirheumatic activity of curcumin (diferuloyl methane) 1200 mg/day with phenylbutazone 300 mg/day. Subjective and objective assessment in patients who were not taking corticosteroids just prior to the study showed signifitant (P<005) improvement in morning stiffness, walking time and joint swelling, following two weeks of curcumin or phenylbutazone therapy. Grip strength, articular index and ESR did not change following administration of either of the compounds. Although a significant improvement was noted in both the groups by the observer, patients assessed significant improvement only with phenylbutazone.
- Publication
Indian Journal of Medical Research, 2013, Vol 138, Issue 1, p632
- ISSN
0971-5916
- Publication type
Academic Journal