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- Title
In vitro evaluation anti bacterial activity of Coriandrum sativum extract in reducing Streptococcus mutans count.
- Authors
Pillay, Sarojini Ramya; Geetha, R. V.
- Abstract
Introduction: Coriandrum sativum L. is a medicinal plant, belonging to the family Umbelliferae/Apiaceae. The leaves and seeds of the plant are widely used in folk medicine. The C. sativum extracts possess promising antibacterial, antifungal, and antioxidative activities as various chemical components in different parts of the plant, which thus play a great role in maintaining the shelf life of foods by preventing their spoilage. The aim is to investigate the effect of C. sativum in reducing Streptococcus mutans count. Materials and Methods: The test organism used was S. mutans. The organism was isolated from saliva sample using selective media Mutans-Sanguis Agar (HiMedia M977) and maintained in Nutrient Agar Slope at 4°C. Agar plate dilution technique was followed to screening the activity of C. sativum extract in reducing the S. mutans count. Results: The antibacterial activity of the C. sativum at different concentrations was screened by agar dilution technique, and the bacterial growth was recorded as colony-forming units. The results are the plate with extract at concentration 1000 µg/ml and 2000 µg/ml which did not show any bacterial growth but the plates 250 µg/ml and 500 µg/ml showed bacterial growth which was decreasing. Conclusion: Hence, it can be concluded that C. sativum extract reduces the count of S. mutans and thus can be used to treat dental caries by adding it in toothpaste and mouthwash.
- Publication
Drug Invention Today, 2018, Vol 10, p2909
- ISSN
0975-7619
- Publication type
Academic Journal