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- Title
Influence of zingiberene on the biofilm formation of Streptococcus mutans.
- Authors
Noufal, Z. Mohamed; Gayathri, R.; Priya, V. Vishnu
- Abstract
The aim is to study the antimicrobial effect of zingiberene species biofilms and the biocompatibility of this modified dental material. Materials and Methods: Streptococcus mutans UA159 were cultured in brain heart infusion with the condition of 37°C anaerobically (5% CO2, 90% N2, and 5% H2). The final inoculum for biofilm formation was composed of bacteria (10,000,000 colony-forming unit/ml each) in 2 ml medium with 50 mM piperazine-1,4-bisethane sulfonic acid and 0.2% sucrose in 24-well plates with specimens placed at 37°C aerobically for 72 h, and the media were changed every 24 h. Results: Minimum inhibitory concentration of zingiberene was found to be 1 mg/mL, where it exhibits 20% inhibition as compared to the moisture control vancomycin. Conclusion: Zingiberene exhibited an antimicrobial activity in biofilm formation analyzed using S. mutans.
- Publication
Drug Invention Today, 2019, Vol 12, Issue 6, p1261
- ISSN
0975-7619
- Publication type
Academic Journal