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- Title
Structural annotation of hypothetical proteins of Streptococcus mutans.
- Authors
Aparnaa, M.; Priya, V. Vishnu; Gayathri, R.
- Abstract
Introduction: Streptococcus mutans is one of the serious pathogens, facultative Gram-positive, anaerobic cocci predominantly found in the human oral cavity known to be involved in promoting tooth decay. Although the genome of this bacterium is already sequenced, there still remain proteins for which neither the function nor the structures are known yet. Therefore, in this study, we will be performing structural annotation of the hypothetical proteins present in S. mutans to find proteins that are similar in fold for further understanding. Materials and Methods: The FASTA sequence of the selected hypothetical protein of S. mutans was subjected to structural annotation using the online server HHpred. Results and Conclusion: It was found that the hypothetical proteins which were selected had glucosyltransferase function and structural annotation supported the finding.
- Publication
Drug Invention Today, 2019, Vol 11, Issue 9, p2108
- ISSN
0975-7619
- Publication type
Academic Journal