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- Title
Anticaries inhibition test of strawberry (Fragaria ananassa) and apple (Pyrus malus L.) fruit juices on Staphylococcus aureus and Streptococcus mutans clinical isolates.
- Authors
Kusuma, Sri Agung Fitri; Yulianto, Asep Nurrahman; Sulistiyaningsih
- Abstract
Objective: The aim of this study was to highlight the anticaries potential of strawberry (Fragaria ananassa) and apple (Pyrus malus L.) fruit juices on Staphylococcus aureus and Streptococcus mutans clinical isolates. Materials and Methods: The fruits were locally cultivated fruits from Indonesia. All fruits were prepared to be processed as fruit juices using a mechanical juicer and followed by juice pasteurization. The fresh juices were then analyzed to screen the phytochemical compounds using the standard methods. Each of the fruit juices was tested to S. mutans and S. aureus clinical isolates at eight different concentrations with a two-fold serial dilution ranging from 50 to 0.78125% v/v using a microdilution method. Results: There were alkaloids and quinones in apple juices, in addition to other bioactive compounds which also present in strawberries juices, such as flavonoids, polyphenol, and tannins. The lowest concentration values to inhibit both S. aureus and S. mutans clinical isolates were exhibited by strawberries juice, ranging at 31.25-62.5 µg/mL to S. aureus and 62.5-125 µg/mL to S. mutans. The data showed that the S. aureus clinical isolates were more sensitive to be inhibited by strawberry juices than S. mutans clinical isolates. Meanwhile, the susceptibility of those bacteria against apple juices revealed the same minimal concentration value, ranging at 250-500 µg/mL. Conclusion: Thus, the strawberry juices can be recommended as a daily healthy beverage to promote human health, especially to avoid dental caries infected by S. aureus and S. mutans.
- Publication
Drug Invention Today, 2020, Vol 14, Issue 7, p1258
- ISSN
0975-7619
- Publication type
Academic Journal