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- Title
Hepatitis B Immunization Status of Health Care Personnel.
- Authors
S., Khristi Purvi; M., Patel Rupal; M., Modi Chirag
- Abstract
Background & objectives: Post-vaccination anti-HBsAg antibody titer measurements among Health Care Personnel (HCP) are not being done routinely at present. The present study was carried out to assess the post vaccination immunization status of HCP and to find an association between demographic & host factors and level of immunity. Methods: Cross-sectional prospective study was conducted at Shree Krishna Hospital, Karamsad. Information on Hepatitis B Virus (HBV) vaccination status and demographic details of HCP were collected using a structured proforma through verbal interviews and hospital information system. Anti-HBs antibody titre was determined by Enzyme Linked Immunofluorescent Assay (ELFA). Results : They were analysed using Pearson Chi2 test and Fisher's exact test. Results: Among 505 participants, 96.4% developed protective antibody titres (= 10 mIU/ml) after primary vaccination. Following revaccination of participants with insufficient titres, 100% developed protective antibodies. There were no non-responders in the study. There was a significant association between anti-HBs antibody titres and duration after last dose of vaccine (p = 0.01) whereas no correlation was found between antibody titres and gender, age group, BMI & category of HCP. conclusions: HBV vaccination showed an excellent response following primary vaccination. For HCP with insufficient titres after primary vaccination, re-vaccination and re-testing is recommended.
- Publication
National Journal of Integrated Research in Medicine, 2018, Vol 9, Issue 4, p37
- ISSN
2230-9969
- Publication type
Academic Journal