We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Protective Effect of Vitamin E Against Hepato-nephrotoxic Oxidative Stress Induced by Isoprinosine Toxicity.
- Authors
Shams, Gamal E. A. M.; Said, Ahmed A.; Omar, Nagah E. M.; Lotfy, Ahmed M.
- Abstract
Isoprinosine was approved that it had hepatic and renal disorder in rabbits. This review covers key studies of protective effects of vitamin E (18.7 mg/kg P. O.) against isoprinosine (163.3 mg/kg P. O.) toxicity for 21 days when vitamin E was co-administered with isoprinosine. Blood samples were collected and the protective effect of vitamin E onbiochemical constituents in serum such as liver injury biomarkers as serum ALT, AST and ALP, kidney injury biomarker as serum creatinine and urea and oxidative stress biomarkers such as serum SOD, GPX and MDA. The obtained results indicated that vitamin E has protection effects through prohibiting the raise in liver and kidney injury biomarkers and oxidative stress biomarkers.
- Publication
Indian Journal of Public Health Research & Development, 2020, Vol 11, Issue 4, p591
- ISSN
0976-0245
- Publication type
Academic Journal