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- Title
The Effect of Wuluh Starfruit Leaf Extract (Averrhoabilimbi. L) on Malondialdehyde (MDA) Levels in Male Rats (Rattus Norvegicus) Hyperglycemia Model.
- Authors
Nanlohy, Clara; Adriani, Merryana; Bambang Wirjadmadi, R.
- Abstract
Starfruit leaf extract (Averrhoabilimbi. L) contains flavonoids as antioxidants that can prevent increased levels of Malondialdehyde (MDA) in hyperglycemia. Starfruit leaf extract can reduce oxidative stress conditions that trigger an increase in MDA levels. This study wanted to determine the effect of giving starfruit leaf extract on MDA levels in hyperglycemia rats from Wistar strain. This study was a completely randomized experimental design using 30 Wistar hyperglycemia rats for 14 days. The treatment group was given starfruit leaves extract of 200 (P1), 400 (P2) and 800 mg per kg of body weight (mg/kg bw) (P3) per day. Furthermore, on the 15th day, MDA levels were measured using a spectrophotometer. The results showed that there was an effect of giving starfruit leaf extract with various doses on MDA levels (p = 0.001), with an effective dose of P1 because it could prevent an increase in MDA levels.
- Publication
Indian Journal of Public Health Research & Development, 2020, Vol 11, Issue 4, p682
- ISSN
0976-0245
- Publication type
Academic Journal