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- Title
Long Term Oral Contraceptive Administration is Associated with Low Serum Levels of Nitric Oxide, Vitamin C and Vitamin E.
- Authors
Hassan, Aseel S.; Al-Salih, Raid M. H.; Al-Naser, Alaa H.
- Abstract
Background: Oral contraceptives are now commonly used by women worldwide as a method for preventing pregnancy. In addition, it was proposed that women taking these drugs require supplementary vitamin E. The aim of this study was to identify changes in serum levels of nitric oxide, vitamin C and vitamin Einwomen taking oral contraceptives for more than three years. Method: The study included (60) women using these tablets and (58) healthy women used as control group. Levels of nitric oxide, vitamin C, vitamin E were estimated in all women participants. In order to estimate the effect of age on levels of nitric oxide, vitamin C and vitamin E, women were divided into two groups: thirteen women aged (18-35) years and thirteen of women aged (36-45) year, remarked to it with symbols (A and B). These groups were compared with two groups of nonuser’s women: twenty-nine of women aged (18-35) years and twenty-nine of women aged (36-45) year, remarked to it with symbols (AC and BC). Results: There was a significant decrease in levels of nitric oxide, vitamin C and vitamin E) (P≤0.05) in all women who were taking oral contraceptives when compared with control women. In addition, the results illustrated significant elevation in nitric oxide, vitamin C and (vitamin Elevels (P≤0.05) in the two groups of user’s women when compared with the control groups. Also, it showed none significant elevation in nitric oxide in group (B) in comparison with group (A) (P≤0.05), while no significant differences were seen in vitamin C and vitamin E levels (P≤0.05) between groups (A) and (B) and control groups. Conclusion: The results of this study indicated that the use of combined oral contraceptives resulted in low levels of nitric oxide, vitamin C and vitamin E.
- Publication
Indian Journal of Public Health Research & Development, 2020, Vol 11, Issue 4, p1514
- ISSN
0976-0245
- Publication type
Academic Journal