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- Title
Anti-Inflammatory activity of Anaphyllum wightii Schott by membrane stabilization method.
- Authors
Dharsana, J. N.; Mathew, S. R. Molly
- Abstract
Anaphyllum wightii Schott (Family-Araceae) commonly known as Keerikizhagu in Malayalam, found in Southern Western Ghats. Anaphyllum wightii Schott is listed as an endemic and threatened species of South India. Tribal communities (Kani Tribes, Malasars, Kadars, Pulaiyars, Madhuvars) use mainly the rhizome of this plant as food and as an antidote against snake bite. The present study aimed at preliminary evaluation of phytochemical and anti- inflammatory study of various extracts of tuber of Anaphyllum wightii Schott by in vitro HRBC membrane stabilizing activity. Chloroform and aqueous extracts of Anaphyllum wightii were found to have significant anti-inflammatory activity. The chloroform and aqueous extract of Anaphyllum wightii showed potent anti-inflammatory activity when comparing with the standard drug Indomethacin, perhaps due to the presence of secondary metabolites like alkaloids, steroids, flavonoids, phenols and saponins.
- Publication
International Journal of Pharmacy & Life Sciences, 2014, Vol 5, Issue 4, p3474
- ISSN
0976-7126
- Publication type
Academic Journal