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- Title
Synthesis of Lactosidated Derivatives of Genistein.
- Authors
Song Guo-hui; Deng Ze-yuan; Cao Shu-wen; Yu Yan-ying; Liu Rong
- Abstract
To improve the targeting activity of genistein in vivo, chemical modification for genistein was carried out by using lactose, which has the potential selective affinity to the surface receptors of cancer cells. Two new compounds, genistein 7-O-β-D-lactoside (4) and genistein 7,4'-di-O-β-D-lactoside (5), were synthesized from unprotected genistein by means of phase transfer catalysis. They were characterized by IR, ¹H NMR, 13C NMR and MS spectral data.
- Publication
Natural Product Research & Development, 2007, Vol 19, Issue 6, p948
- ISSN
1001-6880
- Publication type
Academic Journal