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- Title
低频脉冲电磁场联合唑来膦酸对骨质疏松性股骨粗隆骨折术后的影响.
- Authors
叶林; 方钦正; 董金波
- Abstract
Objective To investigate the effect of low frequency pulsed electromagnetic field (LFPEF) combined with zoledronic acid on postoperative osteoporotic femoral osteotomy. Methods From April 2013 to April 2016,128 cases of osteoporotic femoral osteotomy were randomly divided into treatment group and control group. Both groups received proximal femoral nail anti-rotation (PFNA) treatment. The patients in the control group were treated with zoledronic acid and in the treatment group treated with zoledronic acid in combination with LFPEF after surgery. Visual analogue pain scores (VAS) ,hip function scores (Harris) , fracture healing time,bone density of femoral neck and lumbar spine,bone metabolism and adverse reactions during treatment were compared between the two groups. Results The VAS scores of the two groups were significantly lower at 1,3 and 6 months after operation,and scores of the treatment group were lower than those of the control group (P < 0. 05) . The Harris scores of the two groups were significantly higher at 3 and 6 months after operation,and the scores of the treatment group were significantly higher than those of the control group (P < 0. 05) . The time of fracture healing in the treatment group was significantly lower than that in the control group (P < 0. 05) . The bone mineral density of femoral neck and lumbar vertebrae had greater improvement in the treatment group than in the control group at 6 months (P < 0. 05) . The levels of CTX-I and TRACP-5b were significantly lower in the two groups compared with pre-operation (P < 0. 05) ,and the decrease in the treatment group was greater. There were no significant differences in the adverse reactions between the two groups (P > 0. 05) . Conclusion LFPEF combined with zoledronic acid is a safe and effective method for the treatment of osteoporosis in elderly patients.
- Publication
Chinese Journal of Osteoporosis, 2018, Vol 24, Issue 7, p914
- ISSN
1006-7108
- Publication type
Academic Journal
- DOI
10.3969/j.issn.1006-7108.2018.07.015