We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Boy kısalığı olan çocukların serum ürotensin 2 düzeylerinin igf-1 ile ilişkisi.
- Authors
Yayla, Muhammed; Çetin, Damla; Üstebay, Sefer; Bozkurt, Hayrunisa Bekis; Ertekin, Ömer; Üstebay, Döndü Ülker
- Abstract
Objective: In this study, we aimed to evaluate the correlation between endogenous substances responsible for growth such as IGF-1 and IGFBP-3 by investigating serum levels of Urotensin 2 in children with short stature. Material and Methods: In this study, 150 patients (short stature) and 30 healthy children were evaluated. These were divided into 5 groups, including control, family short stature, structural short stature, malnutrition and celiac disease. The IGF-1 and IGFBP-3 levels were determined as low or normal in these groups. Results: Serum Urotensin 2 levels were found to be higher in structural short stature, malnutrition and celiac disease with low IGF-1 levels and familial short stature with normal IGF-1 levels than control. According to IGFBP-3 levels, Urotensin2 levels were higher in all groups compared to control. Conclusion: In our study, Urotensin 2 may play a role in the pathophysiology of growth retardation and shortening in children.
- Publication
Journal of General Medicine / Genel Tıp Dergisi, 2019, Vol 29, Issue 4, p194
- ISSN
1301-191X
- Publication type
Academic Journal