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- Title
Antioxidant and Anti-Atherogenic Properties of Hawthorn Vinegar in Drosophila melanogaster Fed a High-Fat Diet.
- Authors
Sayin, Kubra; Gunes, Eda
- Abstract
Consumption of vinegar has been associated with protection against hyperglycemia, dyslipidemia, and hypertension. Hawthorn is a medicinal plant with hypolipidemic, anti-inflammatory, digestive modulator, antimicrobial, antioxidant, cardiac stimulant, and hypotensive properties. Therefore, Hawthorn vinegar rich in bioactives (epicatechin, triterpene, saponins, oligomeric procyanidins, chlorogenic acid, and flavonoids) may present a greater value as a functional food for the management of lifestyle diseases. Drosophila melanogaster, when placed on a high-fat diet, exhibit decreased life span and increased antioxidant enzymes. In this high-fat diet fly model, the Hawthorn vinegar led to a significant increase in mean life span, antioxidant enzyme activities, and reduction in malonyldialdehyde level. Furthermore, in vitro studies showed inhibition of α-glucosidase and α-amylase, and angiotensin-converting enzyme II activities, the measures of antiglycemic and antihypertensive potentials, respectively.
- Publication
Current Topics in Nutraceutical Research, 2022, Vol 20, Issue 1, p84
- ISSN
1540-7535
- Publication type
Academic Journal
- DOI
10.37290/ctnr2641-452X.2084-89