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- Title
HSP70 mRNA Expression as an Immune Response Changes under Effect of Moderate Intensity Aerobic Exercise.
- Authors
Tartibian, Bakhtyar; Alizadeh, Behrooz; Ma'landish, Abbas; Sirwan Mohammad Amini Khayat
- Abstract
Objective: Heat shock proteins 70 play a significant role in the immune response. Therefore, the purpose of this study was to investigate the response of men's heat shock protein 70 gene expression under the effect of moderate intensity aerobic exercise. Material and Methods: 21 subjects randomly divided into two groups of moderate intensity aerobic exercise (n=10) and control (n=11). Moderate intensity aerobic exercise group were performed exercise training on the treadmill with intensity of 55 to 70 percent of maximum heart rate reserve, 8 weeks, 3 sessions per week at zero slope and minimum temperature of 22 ° C. To measure HSP70 mRNA, Real-time PCR method was used. Data Analysis was used paired samples t-test and two-way ANCOVA. Results: The results indicated that HSP70 mRNA 24 hours after the 8-week aerobic exercise training in comparison with control group and basal levels had non significantly increased (P=0.94). Conclusion: Moderate intensity aerobic exercise leads to an insignificant increase in the HSP70 gene expression that plays significant role in the immune response in defending against diverse environmental threats or stresses.
- Publication
Iranian Journal of Allergy, Asthma & Immunology, 2018, Vol 17, p221
- ISSN
1735-1502
- Publication type
Academic Journal