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- Title
سنتز سبز نانو ذرات نقره با استفاده از عصاره گیاه آلیوم پارادوکسوم و بررسی فعالیت ضد میکروبی آن
- Authors
ترمه رنجبر; زهرا هاشمی; فرشته صادقیان; حمید رضا گلی; محمد آهنجان; محمد علی ابراهیم زاده
- Abstract
Background and purpose: Microbial resistance against antibiotics is increasingly growing, therefore, it is necessary to develop new remedies. Silver nanoparticles have significant antibacterial properties and synthesis of silver nanoparticles mediated by plant extracts could be considered as an alternative in treatment in various infections. Materials and methods: In this study, silver nanoparticles were synthesized using Allium paradoxum extract. Optimum temperature, concentration, and also optimum pH for production of silver nanoparticles were established. Formation of the particles was investigated by UV-vis spectra, EDS, XRD, and SEM techniques. The MIC and MBC values of the particles against several gram-positive and gramnegative bacteria strains were determined. Results: Optimum condition for synthesis of silver nanoparticles was at 85°C, pH 12, 5 mM concentration, and 30 minutes after adding the extract solution to silver nitrate solution. The particles remained stable until two months after synthesis. The approximate size of silver nanoparticles was 30 to 40 nanometer. Nanoparticles shows strong antibacterial effects against Pseudomonas aeruginosa, and moderate antibacterial activity against Staphylococcus aureus and Escherichia coli. Conclusion: In this study, A. paradoxum was found as a good reducing and coating agent in green synthesis of silver nanoparticles. These particles showed strong antibacterial activities Therefore, they can have high potential for use in biological fields.
- Publication
Journal of Mazandaran University of Medical Sciences (JMUMS), 2020, Vol 29, Issue 182, p1
- ISSN
1735-9260
- Publication type
Academic Journal