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- Title
The Enactive Paradigm 33 Years Later.
- Authors
Vaz, Nelson M.; Ramos, Gustavo C.; de Castro Jr., Archimedes B.
- Abstract
Upshot • According to the biology of cognition and language (Maturana's approach), the immune system is not a cognitive system and the defining of a cognitive paradigm is not what we understand as a Maturanian approach to immunology. The true cognitive actions in immunology are performed by immunologists acting as observers, not by body organs or systems. Stimuli and responses are not adequate concepts in the description of systems. As a closed network of cellular/molecular interactions, the immune system yields patterns of activity, as is transparent in robust conserved profiles of reactivity of natural immunoglobulins, as investigated by Nóbrega et al. and Cohen et al., which offer the opportunity to unravel its natural, spontaneous activity. Dietary materials, products of the commensal microbiome, are the most abundant and common elements continuously incorporated into the network activity and, thus, also represent an important avenue of investigation.
- Publication
Constructivist Foundations, 2011, Vol 6, Issue 3, p345
- ISSN
1782-348X
- Publication type
Academic Journal