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- Title
Voće i povrće kao biokatalizatori za dobivanje kiralnih spojeva.
- Authors
Čiča, Karla Hanousek; Mrvčić, Jasna; Stanzer, Damir; Jakovljević, Tamara; Redovniković, Ivana Radojčić
- Abstract
Due to better efficiency and safety the need for enantiomerically pure chiral compounds is increasing, especially in the pharmaceutical industry. To meet these needs, new, more efficient and cheaper but also environmental-friendly methods of their preparation are needed. Accordingly, great attention has been drawn to biocatalysts in which microorganisms or theirs enzymes are used as biocatalysts. Recently, the scientific community turned to research on the use of fresh, intact plant material as a biocatalyst. The use of plant material does not require the addition of expensive cofactors since various enzyme systems and necessary cofactors, and their regeneration system already exists in plant tissue. Depending on the plant used (fruits, vegetables, spices), either enantiomers may be obtained in high yield and with high enantiomeric excess, which is a critical factor for the development of biologically active compounds and their bioactivity. In this paper, various studies of different plant species parts as biocatalysts in stereoselective transformations of compounds to obtain enantiomerically pure chiral compounds are presented. The use of plants as a biocatalytic systems is in accordance with green chemistry principles and represents a significant alternative to synthetic chemical transformations that would meet the needs of ecological and economic.
- Publication
Croatian Journal for Food Technology, Biotechnology & Nutrition / Hrvatski Casopis za Prehrambenu Tehnologiju, Biotehnologiju i Nutricionizam, 2018, Vol 13, Issue 3/4, p70
- ISSN
1847-3423
- Publication type
Academic Journal
- DOI
10.31895/hcptbn.13.3-4.11