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- Title
Visceral Adiposity is Associated with Increased Risk of Anastomotic Leakage Following Surgery for Colorectal Cancer.
- Authors
Yeung, Trevor M.; Slater, Andrew; Mortensen, Neil J.
- Abstract
INTRODUCTION This study investigates if body fat parameters, including visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), total adipose tissue (TAT) and body mass index (BMI), are correlated with increased risk of complications following surgery for colorectal cancer. METHODS Retrospective study of 54 consecutive patients undergoing elective resectional surgery for colorectal cancer with curative intent. A consultant radiologist reviewed all pre-operative CT scans and calculated body fat parameters using GE software. Primary outcomes were anastomotic leakage and 30 day mortality. Secondary outcomes included length of operation, number of lymph nodes retrieved, medical complications and duration of hospital stay. RESULTS There were 5 leaks (93%) and 3 deaths (5.6%). Out of the four fat parameters, only VAT was significantly associated with an increased risk of developing anastomotic leakage (P=0.0341). The fat parameters were not significantly associated with any other outcome. Although male sex was associated with higher VAT (p=0.001), it was not an independent risk factor for leakage (p=0380). CONCLUSION Increased VAT is associated with a greater risk of anastomotic leakage following resection surgery for colorectal cancer. Further studies are warranted to investigate if pre-operative radiology may be used to stratify high-risk patients who may benefit from a temporary diverting stoma.
- Publication
Journal of Surgical Radiology, 2011, Vol 2, Issue 2, p188
- ISSN
2156-213X
- Publication type
Academic Journal