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- Title
Polypodium Vulgare L.: A valuable cardioactive medicinal plant.
- Authors
Nami, Saeed Reza; Javadi, Behjat
- Abstract
Objectives: Polypodium vulgare L. (Polypodiaceae, Common name: Polypody, Persian name: Baspayak, Basfayaj) is a valuable medicinal plant in Iranian Traditional Medicine (ITM). Jorjani in his great masterpiece "Zakhire Kharazmshahi" mentioned the rhizomes of this plant as a cardioactive plant. Avicenna believes that polypodyacts is an exhilarant, as well as a potent expeller of black bile from heart and other body organs. In this article, we aim to review pharmacological studies supporting cardiac activities of this plant. Materials and Methods: The most popular bibliographic databases were searched for pharmacological data on the cardiovascular activity of Polypodium vulgare. Results: Pharmacological studies demonstrated that Polypodium vulgare has antioxidant, anti-inflammatory, hypotensive and antihypercholesterolemic effects. Interestingly, this plant has been reported to exert positive inotropic and chronotropic, as well as antiarrhythmic effects in animal studies. Ecdysteroids, which are important phytochemicals occurring in this plant, have been shown to prevent myocardial ischemia. Polypodium vulgare also has antiatherosclerotic effects. Conclusion: Polypodium vulgareis is a valuable cardioactive plant, which can be the subject of further animal and clinical studies to enrich and expand our understanding of its cardiovascular efficacy.
- Publication
Avicenna Journal of Phytomedicine, 2015, Vol 5, p112
- ISSN
2228-7930
- Publication type
Academic Journal