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- Title
Does continuous glucose monitoring system detect diabetic range hyperglycemia in women with prediabetes?
- Authors
Garg, Dinesh; Hesarghatta, Asha shyamsunder; Thomas, Nihal; Jeyaraman, Kanakmani; Nithya, Devanithi; Samue, Prasanna
- Abstract
Introduction: The current diagnosis of prediabetes by oral glucose tolerance test (OGTT) involves measurement of plasma glucose values at two-time points. With the availability of continuous glucose monitoring (CGM),it is now possible to record glucose values every 5min for 72 h. CGM may unravel diabetic range glucose levels in prediabetic subjects. Identification of such an unrecognized hyperglycemia will change the classification of patients from prediabetes to diabetes, and will also have treatment implications. Aims and Objectives: To assess whether CGMS can detect diabetic range glucose levels in prediabetic subjects. Materials and Methods: After informed consent, prediabetic women (based on OGTT)were connected to a CGMS (Medtronic ipro) device for 72 h. Family history of diabetes and anthropometric parameters were recorded. Subjects recorded their dietary intake, physical activity, and blood-glucose levels with a glucometer periodically according to a set proforma.(IRB Min no. 7495 dated 07.06.2011). Results: Fifteen eligible women were enrolled over a period of 6months. The mean age was 36.13 years (SD 9.1), Mean Body Mass Index (BMI) was 31.54 kg/m2 (SD 7.86), and waist circumference was 103.07 cm (SD 16.05). Eight subjects were overweight and six were obese. Three subjects had impaired fasting glucose (IFG), two had impaired glucose tolerance (IGT) and ten had both IFG and IGT. The mean fasting glucose was 107.99 mg/dl (SD 8.85), 2h post 75g of glucose was 154.80 mg/dl (SD 21.90) and HbA1C was 5.74% (SD 0.33, range 5.1-6.3%). None of the subjects had diabetic range hyperglycemia. Conclusion: CGMS failed to detect diabetic range hyperglycemia in women with prediabetes (by OGTT).
- Publication
Indian Journal of Endocrinology & Metabolism, 2012, Vol 16, pS522
- ISSN
2230-8210
- Publication type
Academic Journal