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- Title
Cardioprotective role of Aloe vera in diabetic rabbits.
- Authors
Dahiya, Kiran; Sethi, Jyoti; Gupta, Anupama; Ghalaut, Veena Singh; Sood, Sushma; Dhankhar, Rakesh
- Abstract
Objectives: Diabetes is associated with increased risk of coronary artery disease. Avariety of Indian herbs including Aloe vera have been found to possess antihyperglycemic property. To assess the role of Aloe vera in prevention of cardiovascular disease in alloxan induced diabetes and compared with healthy controls. Methods: The ratio of high density lipoprotein cholesterol/ low density lipoprotein cholesterol (HDL-C/ LDL-C), homocysteine and ischemia modified albumin levels were estimated in healthy, diabetic and diabetic rabbits who were administered Aloe vera leaf gel extract for three weeks. Results: The HDL-C/ LDL-C ratio was found to be increased while homocysteine and ischemia modified albumin decreased in diabetes as compared to controls. The results reversed with administration of Aloe vera in diabetic rabbits. The antioxidant property of constituents present in Aloe vera may be responsible for these findings. Conclusion: Aloe vera supplementation in diabetics may help in prevention of cardiovascular complications.
- Publication
Asian Journal of Pharmaceutical & Biological Research (AJPBR), 2012, Vol 2, Issue 2, p147
- ISSN
2231-2218
- Publication type
Academic Journal