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- Title
Engineered T cells towards TNFRSF13C (BAFFR): a novel strategy to efficiently target B‐cell acute lymphoblastic leukaemia.
- Authors
Turazzi, Nice; Fazio, Grazia; Rossi, Valentina; Rolink, Antonius; Cazzaniga, Giovanni; Biondi, Andrea; Magnani, Chiara F.; Biagi, Ettore
- Abstract
The article looks at a report regarding strategy to efficiently target B-cell acute lymphoblastic leukaemia and receptor for B-cell activating factor. It mentions over-expressed in a wide range of B-cell neoplasms including B-cell acute lymphoblastic leukaemia (B-ALL) but is undetectable on B-cell precursors. It also mentions TNFSF13B also detected within the leukaemic niche promoting tumoursurvival, proliferation and chemoresistance.
- Publication
British Journal of Haematology, 2018, Vol 182, Issue 6, p939
- ISSN
0007-1048
- Publication type
Academic Journal
- DOI
10.1111/bjh.14899