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- Title
The Age of Omics‐Driven Precision Medicine.
- Authors
McColl, Eliza R.; Asthana, Rashi; Paine, Mary F.; Piquette‐Miller, Micheline
- Abstract
Numerous SNPs have been linked to altered blood/tissue drug concentrations and increased adverse drug effects.[4] Likewise, SNPs can alter either exposure or binding to drug receptors and other targets, thus impacting therapeutic effects. A subtype of proteomics, chemoproteomics, is arguably one of the most promising applications of omics to the field of drug discovery. This program will also identify causes of intersubject variability, disease susceptibility, and drug responses by taking into account biology, environment, and lifestyle choices ( B Figure b 1). 11 Moellering, R.E. & Cravatt, B.F. How chemoproteomics can enable drug discovery and development.
- Publication
Clinical Pharmacology & Therapeutics, 2019, Vol 106, Issue 3, p477
- ISSN
0009-9236
- Publication type
Academic Journal
- DOI
10.1002/cpt.1532