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- Title
Dermatitis herpetiformis.
- Authors
Nicolas, Marie Eleanore O.; Krause, Patricia K.; Gibson, Lawrence E.; Murray, Joseph A.
- Abstract
Dermatitis herpetiformis (DH), a particularly pruritic bullous skin disease that predominantly affects the extensor surfaces of elbows, knees, buttocks, back, and scalp, is one part of a spectrum of gluten-sensitive disorders that includes celiac disease (CD) and possibly some forms of IgA nephropathy and gluten-sensitive ataxia. DH affects men slightly more frequently than women. In a majority of cases its onset is between the second and fourth decades of life. However, it can appear in later years and even in childhood. Childhood DH is rare and its true prevalence and incidence unknown because it was confused with linear IgA bullous dermatosis and chronic bullous disease of childhood before immunofluorescence studies became routine. DH is usually suspected because of the classic skin presentation, but confirmation requires careful immunofluorescence staining, particularly of perilesional biopsy specimens. Specimens taken at typical DH distribution sites usually give the best yield.
- Publication
International Journal of Dermatology, 2003, Vol 42, Issue 8, p588
- ISSN
0011-9059
- Publication type
Academic Journal
- DOI
10.1046/j.1365-4362.2003.01804.x