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- Title
Acute Effects of Resistance Exercise on Insulin Sensitivity.
- Authors
Black, Laurie E.; Swan, Pamela D.; Alvar, Brent; Pomeroy, Jeremy
- Abstract
Insulin sensitivity and beta-cell function are both key factors in the development of type 2 diabetes mellitus. Physical activity as part of lifestyle modification can reduce the risk of developing diabetes by 58% in people with prediabetes. The primary mechanism for this risk reduction appears to be through increases in insulin sensitivity and preservation of beta-cell function. Resistance exercise (RE) may be a physical activity option to improve acute insulin sensitivity (Si). To evaluate the effects of various RE protocols on 24-hour post exercise Si, 7 participants (mean age 34 ± 10 yrs) with impaired fasting glucose (IFG) completed four separate bouts of RE under moderate intensity (MI) (65% 1-RM) or high intensity (HI) (85% 1-RM) conditions within the confines of single set (SS) and multiple set protocols (MS). Intravenous fasting blood was taken at baseline and 24-hours post exercise for each exercise. condition to measure fasting plasma glucose (GO) and fasting serum insulin (10) and calculate Si (HOMA-IR = (GO*I0)/104). A minimum of 3-days washout was given between each exercise protocol. A4-way ANOVA with repeated measures was performed to compare Si within subjects ant. between treatments. All of the exercise protocols improved subsequent Si (P = 0.045). There was no significant (P=0.57) time by trial interaction. This indicates that RE is efficacious to acutely increase Si. Although not statistically significant, these preliminary data suggest that perhaps volume is more important than intensity for RE to improve Si in individuals with IFG. This research was funded in part by an ASU Graduate and Professional Student Association (GPSA) Research Grant.
- Publication
Diabetes, 2007, Vol 56, pA639
- ISSN
0012-1797
- Publication type
Academic Journal