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- Title
Total intravenous anaesthesia (TIVA) with dexmedetomidine versus nalbuphine in combination with propofol in upperlimb orthopaedic closed manipulation procedure-a comparative study in a tertiary health care centre in Tripura.
- Authors
DAS, RUPAMAY
- Abstract
Background & Aims: The study was planned with the aim of generating comparison profile regarding effects of dexmedetomidine and nalbuphine in combination with propofol while providing more effective stability of intra-procedural haemodynamics and post procedural pain and sedation in upperlimb closed manipulation procedure. Methods: It was an observational analytical study with longitudinal design. The study duration was one and half years. Patients of either sex, normalbodymassindexand age between 20-60 years participatedas study population. 60 cases weredevided into two groups and coded as group D and group N. Both the groups received uniform premedication with Injodansertron 8mg I.V and Inj. omeprazole 40 mg I.V. Group D received Inj. propofol (1%) 1.5mg/kg plus Inj. dexmedetomidine 50 µg I.V bolus while group N received inj. propofol (1%) 1.5mg/kg plus Inj. nalbuphine 10mg I.V bolus prior to theprocedure. Results: Intra operative mean arterial pressure (MAP) and heart rate (HR) were significantly higher in group N than group D (p<0.05). No significant difference was recorded regarding respiratory rate and SpO2 in the two groups (p>0.05). Recovery time of orientation was significantly lower in group D (p<0.05). Post procedural perception of pain was significantly lower in group D (p<0.05). Post procedural sedation was lower in group D which was statistically significant (p<0.05). Conclusion: Dexmedetomidine is superior to nalbuphine in respect of more effective intra-procedural haemodynamic stability, recovery of orientation, pain control after procedure and control of sedation after procedure.
- Publication
Indian Journal of Anaesthesia, 2022, Vol 66, pS65
- ISSN
0019-5049
- Publication type
Academic Journal