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- Title
Glycemic Status, Lipid Profile and Proteinuria in Diabetic Nephropathy.
- Authors
Jha, P.; Das, B. K. L.; Shrestha, S.; Majhi, S.; Chandra, L.; Sharma, S.; Baral, N.
- Abstract
Introduction: Diabetic nephropathy is one of the major complications of Diabetes Mellitus characterized by persistent albuminuria, elevated arterial blood pressure, a relentless decline in glomerular filtration rate (GFR) and a high risk of cardiovascular morbidity and mortality.1 Methods: In this study, urinary micro-albumin estimation was done in 177 diabetic patients. This study aims to ascertain association of glycemic status, lipid profile and proteinuria in Type 2 Diabetes Mellitus with nephropathy. Results: Among 177 patients, 26 had frank proteinuria, 79 had micro-albuminuria and 72 were without proteinuria. Increased frequency of proteinuria was seen in male than female. Micro-albuminuria and frank proteinuria was seen more in older age group. The multiple comparisons showed the significantly increased levels of urea, creatinine, fasting blood glucose in micro-albuminuria and overt proteinuria patients in comparison to without proteinuria. Glycated hemoglobin level was increased with the increasing age group particularly in overt proteinuric patients. Conclusions: The glycemic control, monitoring of lipid profile and early urinary protein estimation with better management may delay diabetic nephropathy or its further complications in diabetes mellitus.
- Publication
Journal of the Nepal Medical Association, 2010, Vol 49, Issue 178, p143
- ISSN
0028-2715
- Publication type
Academic Journal
- DOI
10.31729/jnma.115