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- Title
Investigations of Thujaplicin, a Fungicidal Substance in the Heartwood of Thuja plicata D. Don.
- Authors
Rennerfelt, Erik
- Abstract
From heartwood of Western Red Cedar (Thuja plicata D. Don.) Erdtman and collaborators have isolated three isomeric compounds, α-, β-, and γ-thujaplicin, with the empiric formula C10H12O2. These compounds have a strong fungicidal effect upon blueing and decay fungi in malt extract agar. Decay fungi are inhibited in concentrations between 0.001 and 0.002 per cent γ-thujaplicin (10--20 p.p.m.). Phenol, tested in the same way, inhibits the decay fungi in 0.1--0.2 per cent concentrations. Blueing fungi are completely inhibited in a solution of 0.01--0.02 per cent, and considerable inhibition can be observed in a solution of 0.002--0.005 per cent γ-thujaplicin. The growth of the blueing fungi ceased in agar, containing 0.1 per cent phenol. Of the isomeric compounds tested according to the agar diffusion method β-thujaplicin is most toxic, and γ-thujaplicin is some more toxic than α-thujaplicin. Thujaplicin is about as active as sodium pentachlorophenol.
- Publication
Physiologia Plantarum, 1948, Vol 1, Issue 3, p245
- ISSN
0031-9317
- Publication type
Academic Journal
- DOI
10.1111/j.1399-3054.1948.tb07128.x