We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
CRYSTAL STRUCTURE OF THE CIPROFLOXACIN IONIC COMPLEX WITH THE COBALT(II).
- Authors
KUDIYAROVA, А. D.; ASHUROV, J. M.; IBRAGIMOV, A. B.; SABIROV, V. K.; KHODJANIYAZOV, K. U.
- Abstract
Background. Modern science of Uzbekistan expects a tendency to integrate with industry. Obtaining new pharmacologically active compounds becomes relevant in the development of domestic drugs. Improving the quality of these drugs has a decisive interest. In addition, the establishment of accurate geometric characteristics of molecules is important for their practical use and clarifying the structure-activity relationship. Purpose. The purpose of the current investigation was to obtain the new complex of Co(II)ciprofloxacin and determination of its crystal structure. Methodology. X-ray crystallography at 293 K on an Xcalibur R Oxford Diffraction automated diffractometer was used. Originality. The crystal structure and molecular characteristics of Co-ciprofloxacin ionic complex is studied for the first time for the first time. Findings. The crystal structure of Co-ciprofloxacin ionic complex consists of the [Co(H2O)6]2+ tetrahedron and two singly charged (HL)+ cations, two sulfate anions and six water molecules. The ion Co2+ lies on the symmetry axis 2 at the position 4e. It has the octahedral coordination with Co-Ow 2.073 Å (average) and angles Ow-Co-Ow' is 91° (average). Two water molecules surrounding the Co2+ ion and the four O atoms of the sulfate group are disordered into two positions with occupation factors 0.60(1) and 0.40(1) in the cation and 0.46(1) and 0.54(1) in the anion.
- Publication
Uzbek Chemical Journal / O'Zbekiston Kimyo Jurnali, 2021, Issue 2, p63
- ISSN
0042-1707
- Publication type
Academic Journal