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- Title
内源性大麻素系统用于骨质疏松症预防与治疗的 研究进展.
- Authors
王蕾; 杨涛; 耿立成; 孙天威
- Abstract
Osteoporosis (OP) is a kind of systemic bone disease characterized by reduced bone mass and changes of bone microstructure. The incidence rate of OP has been increasing gradually year by year, which has become a severe public health issue. The imbalance of bone metabolism mediated by osteoblasts and osteoclast is an important pathogenesis of OP. The endocannabinoid system (ECS) is widely distributed in bone tissue and participates in regulating multiple biological effects of osteoblasts and osteoclasts, suggesting that ECS may be a potential treatment target of OP. Further study on targeting ESC can provide a new theoretical basis for the clinical treatment of OP. This article reviews the specific role of ECS in regulating the pathogenesis of OP.
- Publication
Tianjin Medical Journal, 2023, Vol 51, Issue 9, p1020
- ISSN
0253-9896
- Publication type
Academic Journal
- DOI
10.11958/20230510