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- Title
Paralysis of the external popliteal sciatic nerve associated with daptomycin administration.
- Authors
Villaverde Piñeiro, L.; Rabuñal Rey, R.; García Sabina, A.; Monte Secades, R.; García Pais, M. J.
- Abstract
Summary: What is known and objective: Peripheral neuropathy has been associated with the administration of certain drugs. Few reports have described the association of daptomycin with the development of peripheral neuropathy, none of them with peroneal nerve involvement. Case summary: We report a case of a 62‐year‐old man who developed external popliteal sciatic nerve paralysis after 22 days of therapy with daptomycin. What is new and conclusion: We present an uncommon and not previously reported adverse event. We have also analysed a possible alteration in a metabolic pathway (ABCB1 gene polymorphisms) that, in some patients, could explain certain drug adverse events. What is new and conclusion: We present an uncommon and not previously reported adverse event. We have also analysed a possible alteration in a metabolic pathway (ABCB1 gene polymorphisms) that, in some patients, could explain certain drug adverse events.
- Publication
Journal of Clinical Pharmacy & Therapeutics, 2018, Vol 43, Issue 4, p578
- ISSN
0269-4727
- Publication type
Academic Journal
- DOI
10.1111/jcpt.12666