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- Title
Unexpected Serious Cardiac Arrhythmias in the Setting of Loperamide Abuse.
- Authors
RASLA, SOMWAIL; AMAND, AMY ST.; GARAS, MARINA K.; EL MELIGY, AMR; MINAMI, TARO
- Abstract
Loperamide (Imodium) is a non-prescription opioid receptor agonist available over-the-counter for the treatment of diarrhea. When ingested in excessive doses, loperamide can penetrate the blood-brain barrier and is reported to produce euphoria, central nervous system and respiratory depression, and cardiotoxicity. There is an emerging trend in its use among drug abusers for its euphoric effects or for self-treatment of opioid withdrawal. We report a case of ventricular dysrhythmias associated with loperamide abuse in a 28-year-old man who substituted loperamide for the opioids that he used to abuse.
- Publication
Rhode Island Medical Journal, 2017, Vol 100, Issue 4, p33
- ISSN
0363-7913
- Publication type
Academic Journal