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- Title
Isolation, Molecular Characterization and Mycochemical Analysis of Aspergillus quadrilineatus.
- Authors
M., Shaila; Begum, Nafeesa
- Abstract
Secondary metabolites of microbial origin, either as pure compounds or crude extracts, provide opportunities for new drug development because of their chemical diversity. The aim of the present study is to isolate Molecular characterization and extract the bioactive compounds from the fungus of A. quadrilineatus (OL979151) in the rhizospheric soil of sunflower and mustard crop fields in Davanagere region. Dilution plate technique was used to isolate the rhizosphere fungi. The total genomic DNA was extracted from isolate of Aspergillus quadrilineatus based on Cetrimide Tetradecyl Trimethyl Ammonium Bromide (CTAB). Mass production of the fungal mat of A. quadrilineatus was established on potato dextrose broth medium. The dried methanol extract of fungus was subjected to HR-LCMS analysis; Methanol extract of A. quadrilineatus fungus shows that the compounds Amobarbital, Pirbuterol, Bambuterol, Cilazaprilat, Oxotremorine, Aminopyrine and Oryzanol as the major constituents. The compounds exhibit analgesic, anti-inflammatory, and antipyretic properties and various therapeutic uses.
- Publication
Journal of Plant Science Research, 2022, Vol 38, Issue 2, p485
- ISSN
0970-2539
- Publication type
Academic Journal
- DOI
10.32381/JPSR.2022.38.02.5