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- Title
THE SEROPREVALENCE OF RUBELLA VIRUS IN WOMEN AND ITS RELATIONSHIP TO ABORTION IN DIYALA GOVERNORATE.
- Authors
Mohsin, Ibtihal Hameed
- Abstract
The contagious childhood viral disease rubella, is caused by rubella virus. Rubella affects both sexes and all ages. Children and adults are mildly affected. This type of infection is called postnatal infection. Rubella is a highly public health problem due to its teratogenic effect which may result in fetal deaths, miscarriages, stillbirths, or may cause fetal multi system damage in the first 16 weeks of pregnancy. This study aimed to determine the prevalence of specific IgM, IgG antibodies to rubella virus in pregnant and non-pregnant women in Diyala governorate and the extent of the virus’s association with abortion. The study was carried out in the city of Baqubah, the center of Diyala governorate, for the period from 1 November 2019 to 30 March 2020 in the Public Health Laboratory in Baquba. The enzyme linked immune sorbent assay (ELISA) technique was used for the determination of the prevalence of IgM and IgG specific antibodies to rubella virus among samples of (pregnant women, non-pregnant women at childbearing ages). As well as studying the effect of some factors on the extent of seroprevalence of specific antibodies, such as (Residence, educational level and the presence of previous miscarriages). The study included 100 women who were classified into two groups: the first group included (50) pregnant women who were also subdivided into two groups (the group of pregnant women with previous miscarriages and the group of pregnant women without previous miscarriages), while the second group included (50) non-pregnant women of childbearing age, who were also subdivided into two groups, the group of non-pregnant women with a previous miscarriage and the group of non-pregnant women without a previous miscarriage. Our results demonstrated that the rate of anti-rubella IgM seropositivity in pregnant women with previous abortion and in women without previous abortions was (36,66% and 20%) respectively, while the rate of anti-rubella IgG seropositivity in pregnant women with previous abortion and in women without abortions was (56.7% and 30%), respectively. The results also revealed that the rate of anti-rubella IgM seropositivity in non-pregnant women with previous abortion and nonpregnant women without abortions was (18.91% and 15.38%) respectively. Also, the rate of anti-rubella IgG seropositivity in non-pregnant with previous abortion and non-pregnant women without abortion was (54.05% and 13.51%), respectively. The highest rate of anti-rubella IgM was recorded in illiterate women and primary school level. In addition, the highest rate of antirubella IgG was found in illiterate women and primary school level. The study also found that the highest rate of anti-rubella IgM seropositivity was reported in urban women when compared to rural women. In conclusion, it can be concluded that there is no effect of age on the seroprevalence of rubella virus antibodies. The prenatal screening for anti-IgG & anti-IgM –rubella antibodies is found to be a necessary procedure for active infections determination, and providing obstetric managements to prevent risks of congenital rubella.
- Publication
Biochemical & Cellular Archives, 2021, Vol 21, Issue 2, p3589
- ISSN
0972-5075
- Publication type
Academic Journal