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- Title
TWO DIRECT SIMPLE VISIBLE SPECTROPHOTOMETRIC ASSAY METHODS OF SOLIFENACIN SUCCINATE IN ORAL TABLET FORMULATIONS.
- Authors
Kiran, M. Madhu; Rambabu, C.
- Abstract
Two direct, simple visible spectrophotometric methods (Method -I & II) were described for the assay of solifenacin succinate in pure and in oral dosage forms. The proposed methods (I&II) are based on the ion association complex reactions between the mentioned drug (solifenacin succinate) and the basic dyes (Methylene blue and Methylene Violet) respectively. Beer-Lambert plots showed good correlation in the concentration range of 2.0-10μg/mL for methods-I &II respectively. The proposed methods were applied to commercially available dosage forms (tablets) of solifenacin succinate and the results were statistically compared with the results obtained by the reported method7 with recovery studies. The proposed methods offered the advantages of being simple and economical that can be applied without the need for expensive instrumentation and reagents in quality control analysis.
- Publication
Rasayan Journal of Chemistry, 2017, Vol 10, Issue 4, p1068
- ISSN
0974-1496
- Publication type
Academic Journal
- DOI
10.7324/RJC.2017.1041812