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- Title
CORALLINE POROUS HYDROXYAPATITE IN PERIODONTAL REGENERATION.
- Authors
George, Joann Pauline; Moghe, Ameya G.; Lazarus, J. Flemingson
- Abstract
Certain marine invertebrates secrete calcium carbonate skeleton with interconnected pores. Corals best present this group of animals. The microstructure of marine invertebrates has been used as a template to make porous structures. Some of these species have average pore diameters of about 500 µm which corresponds to remodelled cancellous bone. Another interesting feature of this coralline porous hydroxyapatite is the degree of interconnectivity between the pores which eliminates the problem of narrowed & dead end pathways that was a limitation with the previous implants. The primary purpose of tissue engineering is repair, regeneration, and reconstruction of lost, damaged or degenerative tissues. Although bone tissue itself shows an excellent ability of bone regeneration, for big bony defect or for such situations that bone healing process is difficult bone grafts are required. .Bone substitutes have filled a niche in periodontal practice by providing defect fillers of variable biological activity. Porous hydroxyapatite has been extensively applied used as artificial bone substitutes. Porous hydroxyapatite have been also been applied for cell loading, as drug releasing agents, chromatography analysis and the most extensively for hard tissue scaffolds. Coralline hydroxyapatite when used as graft material in periodontal defects has the ability to facilitate osteogenesis.
- Publication
Clinical Dentistry (0974-3979), 2012, Vol 6, Issue 5, p38
- ISSN
0974-3979
- Publication type
Academic Journal