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- Title
Bergenin: a versatile and readily available precursor for bioactive modifications.
- Authors
Suqian Cai; Kefeng Zhang; Xiaohua Cai
- Abstract
Bergenin, as a major bioactive ingredient of traditional Chinese medicine bergenia, can be found to be a significant component or a secondary metabolite in many families. Bergenin and its derivatives have aroused great interest because their unique bioactivities and pharmacological properties have been gradually disclosed over the past decades. A great number of bergenin derivatives have been synthesized, and their biological activities have been surveyed to achieve many satisfactory results in recent several years. These studies are beneficial in discovering and identifying novel candidates from bergenin derivatives as potential therapeutic drugs and help us understand their molecular targets and mechanisms of pharmacological action. This present work compiled scattered information on semisynthetic derivatives of bergenin and highlighted their recent advances in bioactive modifications.
- Publication
Journal of Chinese Pharmaceutical Sciences, 2023, Vol 32, Issue 5, p333
- ISSN
1003-1057
- Publication type
Academic Journal
- DOI
10.5246/jcps.2023.05.029