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- Title
Criteria for the Oral Glucose Tolerance Test in Pregnancy.
- Authors
O'sullivan, John B.; Mahan, Clare M.
- Abstract
A group of 752 women were given 100-g oral glucose tolerance tests (GTTs) in pregnancy. Distribution of the resulting Somogyi-Nelson venous blood glucose values proved satisfactory for use in setting up three test criteria of graded severity. The derived criteria were then applied to the gestational tests of 1,013 women selected for periodic GTT's on a long-term basis. A strong correlation was found between the severity of the three original graded classifications and the percentages within each group subsequently developing diabetes (Test Level I only, 6.9%; Test Level II only, 16.1%; Test Level III only, 40.3%). Application of the life table technic re-emphasized this result, with the corresponding 17.2, 29.0, and 60.1 percentages, respectively. The ability to identity future diabetics was in no way diminished by a test of lower positivity in a subsequent pregnancy. Maintaining the initial level of positivity with Test Level II in a repeat pregnancy, on the other hand, doubled this risk. The impressive worth of the oral glucose tolerance test in pregnancy is demonstrated. The criterion considered suitable for routine application consisted of any two or more of the following values being met or exceeded: Fasting, 90 mg/100 ml; l-hour, 165 mg/ 100 ml; 2-hour, 145 mg/100 ml; 3-hour, 125 mg/100 ml.
- Publication
Diabetes Spectrum, 1992, Vol 5, Issue 1, p26
- ISSN
1040-9165
- Publication type
Academic Journal